Chizarira National Park lies on, and south of, the Zambezi Rift Valley escarpment, about 80 km south-east of the small town of Binga, on the southern shore of Lake Kariba. The park is bounded in the north, west and east by Binga, Gokwe and Manjolo Communal Lands and in the south by the Chirisa Safari Area. It falls within Binga District of Matabele land North Province and forms part of the Sebungwe region. It is accessible by dirt roads from Binga, Gokwe and Lusulu. The dramatic Chizarira escarpment rises up 500 m from the Zambezi valley, peaking at 1,434 m on Tundazi Mountain, and drops gradually down to the Busi River in the south of the park (800 m). The escarpment is deeply dissected by gorges through which flow the Mucheni, Luzilukulu (Rhuziruhuru) and Sengwa rivers. The gorges are up to 460 m deep and form a spectacular sight.

Tourists are attracted to the scenery and high wilderness quality of the park. On the top of the escarpment the climate is cooler and wetter than the adjacent Zambezi valley. Rainfall is about 600 mm annually and temperatures can rise to 40°C in the hot dry season. During winter the temperature drops to below 0°C in the river valleys. Along the escarpment the north-facing scree slopes are sparsely vegetated. In contrast, the gentler south-facing slopes are covered with miombo woodland of Brachystegia and Julbernardia. Fire and elephants help to keep the woodlands open. There are numerous grassy vleis, springs e.g. Manzituba, Muchininga and streams originating from the central watershed in the park. Other vegetation-types include mopaneColophospermum woodland, 'sidaga' grassland, Combretum/ Commiphora thickets, and riparian woodland/forest of Acacia/ Trichilia (also containing elements of the Eastern Highlands vegetation)

Chizarira National Park is the third-largest national park in Zimbabwe, and also one of the least known because of its isolated situation on the Zambezi Escarpment.Chizarira provides a wide variety of habitats for birds, with nearly 400 species having been recorded.Chizarira has a huge variety of bird life and hundreds of species have been sighted within the Park, sought after birds recorded include the African broadbill, Livingstone's flycatcher, yellow-spotted nicator, African emerald cuckoo and the rare and elusive African pitta. Chizarira is also home to the Taita falcon which breeds within the Park.