Matusadona National Park is a national park in northern Zimbabwe situated on the southern shore of Lake Kariba. Its area encompasses a combination of pristine and rugged wilderness, which before the Kariba Dam was built and Lake Kariba created was very inaccessible. The creation of the lake caused profound ecological changes. In particular, the availability of grazing on the lakeshore has contributed to an increase in the populations of large mammals large mammal in the park, especially those of elephant and Cape buffalo.

Matusadonha National Park has as its southern boundary the Omay Communal land and the northern boundary is the Lake Kariba shore, the eastern side is the Sanyati Gorge and the Ume River forms the western boundary. Visitors concentrate on visiting the area in the north of the National Park between the Matusadonha hills, which form part of the Zambezi Escarpment, and the lakeshore which is particularly attractive and has a network of gravel roads. South of the Matusadonha hills is mountainous area and remote, with access restricted to tracks from the Binga-Karoi road and the main access road. There are no campsites in this area and a permit is required before entry.

Before the lake was built, Matusadonha was a vast, rugged wilderness with limited access and had been proclaimed a non-hunting area in 1958. It became a Game Reserve in 1963, and in 1975 a National Park comprising some 1,400 square kilometres (540 square miles) of diverse flora and fauna. Matusadona is an Intensive Protection Zone (IPZ) and home to relocated rhinoceros. While the mammals are scarce at the Matusadona National Park except for hippos and crocs in the lake, there is no shortage of birds. White-breasted cormorants and African darters are patrolling the water and diving for fish. Giant African fishing eagles sit on trees. Smaller but colorful kingfishers and bee-eaters divebomb for fish and insects and when you add all the egrets and cranes and storks it's a total birder's paradise.